TRT guides

Testosterone replacement therapy for men, in plain language: the medicines, life on treatment, fertility, labs and access.

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Testosterone medicines compared by route
Medicine	Form	Route	How often	Labeled dose	Label
Injections
Testosterone cypionate	Oil injection	Into a muscle	Every 2–4 weeks	50–400 mg	US label
Testosterone enanthate	Oil injection	Muscle or under the skin	Every 2–4 weeks	50–400 mg	US label
Testosterone propionate	Oil injection	Into a muscle	See guide
Sustanon 250	Oil injection	Into a muscle	Every 3 weeks	250 mg	UK label
Undecanoate injection	Oil injection	Into a muscle	Every 10–14 weeks	1,000 mg	UK label
Skin
Testosterone gel	Gel	On the skin	Once a day	40.5 mg	US label
Compounded cream	Cream	On the skin	See guide
Oral
Oral testosterone	Capsule	By mouth	Twice a day	200 mg	US label
Nasal
Natesto	Nasal gel	In the nose	3 times a day	11 mg	US label
Pellets
Testosterone pellets	Pellet	Under the skin	Every 3–6 months	150–450 mg	US label