CJC-1295 and Ipamorelin Stack: CJC/Ipa, GH Blend, Hulk and Pulse

What is the CJC-1295 and ipamorelin stack?

The CJC-1295 and ipamorelin stack pairs two lab-made peptides that each make the pituitary gland release growth hormone, through different switches. It is usually sold premixed as CJC/Ipa, GH Blend, Pulse or, at some sellers, Hulk. People use it for sleep, recovery and body composition. Nobody has tested the pair together. [10], [22]

CJC-1295 copies the brain's growth-hormone-releasing hormone (GHRH); ipamorelin copies the gut hormone ghrelin at its receptor on the pituitary. Neither is an approved medicine. [10], [12]

The name hides a bigger difference. CJC-1295 with DAC has an add-on that keeps it active for about a week, and it is the only version ever given to people in published studies. CJC-1295 without DAC, also called Mod GRF 1-29, is the version most blends use, and it has never been studied in people. [10], [11] In community education groups, almost every report on either peptide is about this pair, most often a premixed 1:1 vial of the version without DAC.

What's in it, and what else is it called?

The two parts are CJC-1295 (with or without DAC) and ipamorelin. FDA says the inconsistent naming of CJC-1295 is "a safety risk for patients", because labels often do not say which molecule a vial holds. [10]

A nickname does not fix what is in the vial. "Hulk" is CJC-1295 and ipamorelin at some sellers and a different pair at others, and "CJC-1295" on a blend label can mean either version. Only the label's amount for each peptide, and which CJC-1295 it names, tell you what a dose contains. [3], [16], [17], [23]

What is in each blend in this stack?

Most of this stack is sold as a premixed vial. CJC/Ipa is by far the most common name, followed by GH Blend, Hulk and Pulse. All four usually hold CJC-1295 and ipamorelin at 1:1, but the CJC-1295 may be either version, and Hulk can mean a different product entirely.

Amounts below are what labels state. They are not doses, and not proof of contents. [24]

CJC/Ipa

CJC-1295 and ipamorelin in one vial, also written CJC-1295/Ipamorelin or Mod GRF/Ipa. At 1:1, each milligram of powder holds 500 mcg of each peptide.

• Where sellers disagree: on which CJC-1295 is inside and on the ratio. One compounding clinic's page gives two amounts that do not match (see stated amounts). One seller-hosted certificate headed "with DAC" prints the molecular weight of the version without DAC. [23], [10]
• Stated amounts: one compounding clinic's page gives a typical 100–200 mcg of each, five nights a week, but its vial directions (0.25 mL of its 1:2 liquid, Monday to Friday) deliver about 300 mcg CJC-1295 and 600 mcg ipamorelin. A clinic patient sheet gives 200 mcg of each (0.2 mL of its liquid) five evenings a week. See the combination schedules. [2], [26]
• Regulators: FDA inspection reports from 2021 and 2022 record two compounding pharmacies making CJC-1295 and ipamorelin injections from ingredients that were not pharmaceutical grade. An FDA review notes an outsourcing facility's injection with 6 mg/mL of CJC-1295 and 15 mg/mL of ipamorelin. [27], [28], [10]
• Lab reports: two seller-posted reports of 5 mg + 5 mg vials measured 5.41 mg + 5.48 mg (with DAC tested for and not found) and 5.05 mg + 4.62 mg. Each covers one lot sent in by the seller. [25], [29]

GH Blend

A loose name for the same pair, also sold as "GH Stack". Where the page says which CJC-1295, it is the version without DAC. [6], [14]

• Where sellers disagree: whether it is one vial or two, and the amounts in the larger vials.
• Stated amounts: a reference page lists 200–600 mcg of the blend once or twice daily before bed; another seller page lists 75 mcg of each once a day. [6], [30]
• Regulators: no notice we found names GH Blend.
• Related stacks: the classic GH releasers stack covers older growth-hormone peptides such as GHRP-2.

Hulk

Hulk is a seller nickname with no shared meaning. Three of the products we found are CJC-1295 with ipamorelin, but they differ on which CJC-1295, and two other sellers use the name for different peptides. [3], [4], [31], [16], [17]

• Where sellers disagree: on everything, including whether the vial holds CJC-1295 at all. A Hulk with DAC cannot follow the nightly schedules written for the version without DAC; see how the protocols line up. [10], [11]
• What the other versions contain: tesamorelin is a GHRH medicine approved to reduce excess belly fat in adults with HIV-associated lipodystrophy, covered with ipamorelin in the tesamorelin and ipamorelin stack. BPC-157 with TB-500 is the healing and recovery stack. [32]
• Stated amounts: the Hulk pages we checked give no dose.
• Regulators: no notice we found names Hulk. In August 2026 FDA sent warning letters to two companies selling tesamorelin and ipamorelin blends as unapproved drugs. [33], [34]
• Related stacks: the classic GH releasers stack also lists Hulk among the names you may see.

Pulse

One seller's name for a 10 mg vial of CJC-1295 without DAC 5 mg + ipamorelin 5 mg. It also lists a 20 mg vial without saying how it is split, and sells a tesamorelin and ipamorelin blend under another name. The page gives no dose, and no regulator notice names Pulse. [5]

Blends that also contain CJC-1295 and ipamorelin

These add a third or fourth peptide and belong mainly to other stacks. Every draw carries all the parts at the fixed ratio.

A "Sleep Blend" sold by one clinic contains DSIP, CJC-1295 and BPC-157 but no ipamorelin; it belongs to the sleep and circadian stack. [38]

Why do people combine CJC-1295 and ipamorelin?

People combine them because the two peptides press different switches on the same pituitary cells, and studies of other GHRH and ghrelin-type pairs found more growth hormone together than apart. That is a rationale borrowed from other peptides, not proof for this pair. [9], [39]

• Two switches. CJC-1295 acts on the GHRH receptor and ipamorelin on the ghrelin receptor. [10], [12]
• A bigger pulse, claimed. A clinic website says the pair releases 3–5 times more growth hormone than ipamorelin alone. FDA's ipamorelin review quotes the claim without endorsing it, and no study of these two peptides supports it. [22]
• One injection. A premixed vial means one draw a night. [40]
• Goals. In community education groups, people cite sleep, recovery and body composition, often alongside a weight-loss medicine or hormone therapy, which makes any effect hard to credit to the pair.

What does the evidence show?

No study of any kind has given CJC-1295 and ipamorelin together, and each part has little human evidence on its own. [8], [41]

CJC-1295

All human data come from the version with DAC: 67 healthy adults in small 2006 studies, none dosed for more than two weeks, in whom growth hormone and IGF-1 rose for days. The only patient trial stopped in 2006 after a participant's unexplained death. The version without DAC has never been tested in people. [11], [42], [43], [10] Full CJC-1295 evidence

Ipamorelin

Single IV infusions in healthy men (1999) gave one growth-hormone pulse, gone within about 6 hours. IV ipamorelin after bowel surgery (2014) did no better than placebo. Fewer than 100 people are known to have received it in published studies, none by subcutaneous injection. [13], [44], [22] Full ipamorelin evidence

The combination

• Never studied together. We found no human or animal study, case report or registered trial of CJC-1295 (either version) with ipamorelin, and no study of ipamorelin with any GHRH-type peptide. [8], [41]
• The closest evidence uses other peptides. Given into a vein, GHRH with GHRP-6 released more growth hormone than the two added up in healthy men (1990), while GHRH with GHRP-2 was only additive in volunteers (1995). In critically ill adults, a 21-hour GHRH and GHRP-2 drip doubled growth hormone compared with GHRP-2 alone (1997), and in 11 older adults a 24-hour subcutaneous infusion (into the fatty layer under the skin) beat either peptide alone (2004). None used CJC-1295 or ipamorelin, and no pair was given for longer than 24 hours. [9], [39], [45], [46]
• A misreported study. A 2026 review says CJC-1295 with ipamorelin improved muscle strength in steroid-treated mice. The study it matches gave ipamorelin alone, to rats. [47], [48]

How do the CJC-1295 and ipamorelin stack protocols line up?

These are each part's protocol from its own guide's verified table. They are not a stack protocol, and the DAC and non-DAC rows are different drugs: never swap their amounts. [10]

Schedules published for the combination

Each row is a complete schedule from one source, with that source's amounts kept together. The first three rows are the blend table both component guides use.

A few pages pair CJC-1295 with DAC with nightly ipamorelin instead. Those schedules keep the DAC part weekly:

What one draw holds in different vials

A blend dose is set by the vial, the water added and the draw. The same 0.1 mL carries different amounts of each peptide depending on the vial's ratio (arithmetic from listed contents):

How people line them up

Sources describe three styles, never compared: both peptides in one nightly injection on an empty stomach; a dose stepped up every two weeks over a 12-week course; and, with the DAC version, a weekly or twice-weekly CJC-1295 injection alongside nightly ipamorelin. [40], [52], [57], [54] In community education groups, the most common routine is about 250 mcg of each at bedtime, often 5 days on and 2 off; some move the dose to the morning when it disturbs sleep.

Plan it once. A nightly blend, a stepped dose or a weekly and a nightly schedule side by side are easy to mix up.

What are the overlapping risks and interactions?

Both parts raise growth hormone, so their effects can add up, and the pair has never been safety-tested. The shared risks are flushing and heart-rate changes, allergic-type reactions, blood-sugar effects and vials that do not match the label. [10], [22]

• Flushing, heart rate and blood pressure. In the single-dose DAC study, 30% had flushing, warmth and brief drops in blood pressure, and heart rate rose with the dose. FDA reports serious events with CJC-1295, including a faster heart rate and a "systemic vasodilatory reaction" (widespread widening of blood vessels). [11], [42], [62]
• Allergic-type reactions. About 30% had hive-like rashes at the injection site in that study, and FDA lists immune reactions as a concern for both peptides. One person who reacted to a blend later tried each part alone; only CJC-1295 raised a hive. [11], [10], [22], [63] In community education groups, reactions often began on restarting after a break. Hives, swelling of the lips, face or tongue, throat tightness, wheezing or fainting after an injection need urgent medical care. [32]
• Blood sugar and potassium. In the post-surgery ipamorelin trial, high blood sugar was more common than on placebo (14.3% vs 8.6%), and so was low potassium (12.5% vs 3.4%). The short DAC studies found no consistent change in blood sugar. [22], [11]
• Swelling, joint pain, heart and cancer. Growth-hormone labels list swelling, joint pain and numb hands, and carry a tumour warning; none has been measured for either peptide, and the death in the CJC-1295 trial was never explained. [64], [43]
• Wrong or unclear contents. In a 2026 preprint of lab reports, CJC-1295 failed identity testing 9.1% of the time, and seized powders have held altered versions of ipamorelin and Mod GRF 1-29. [24], [65]

Interactions. No interaction between the two peptides, or with other medicines, has been studied; that is an absence of data, not evidence of safety. Other growth-hormone-raising products, such as tesamorelin, MK-677 or growth hormone itself, could add to the same effects, and people on diabetes medicines have extra reason for caution because growth hormone can reduce the body's response to insulin. [64], [32]

Be especially cautious or avoid them in pregnancy or breastfeeding; under 18; with active or past cancer; with diabetes or prediabetes; with heart disease, fainting or fall risk; after any past reaction to a peptide injection; and in competitive sport.

Legal and sport status (checked September 2026):

• United States: neither part is FDA-approved. FDA's advisers voted against allowing either in pharmacy compounding (December 2024 for CJC-1295, October 2024 for ipamorelin), and ipamorelin has been on FDA's safety-risk list for outsourcing facilities since September 2023. Inspection reports have cited compounded CJC-1295 and ipamorelin injections. [66], [67], [62], [27]
• Canada: Health Canada has authorized neither and lists both among unauthorized injectable peptides; a seizure notice listed separate vials labelled "CJC-1295" and "CJC-1295 DAC". [68], [69]
• Australia: both are prescription-only (Schedule 4) and illegal to possess without authority; in August 2026 the TGA reported seizing products that included CJC-1295. [70], [71]
• Sport: the WADA 2026 and 2027 lists name both, CJC-1295 as a GHRH analogue and ipamorelin as a growth hormone secretagogue, prohibited at all times. [72], [73]

What should be monitored?

No official guidance exists. What studies and labels for related medicines measured or flagged:

• Blood work: IGF-1 before and during a course, blood sugar (glucose, HbA1c) and potassium. [11], [32], [22]
• Heart rate and blood pressure: both changed in the DAC studies. Heart rhythm matters too: macimorelin, an approved drug acting on ipamorelin's receptor, lengthens the QT interval on an ECG. [42], [11], [74]
• Side effects and skin: flushing, hives and injection-site reactions. [11]
• Fluid and joints: swelling, joint pain and hand numbness. [64]
• Sleep and appetite: insomnia was more common on ipamorelin than placebo in the post-surgery trial (10.7% vs 5.2%). [22] In community education groups, people also report hunger after doses.

With a blend, a change cannot be pinned on one part. If a reaction appears, stop and talk to a clinician before restarting anything.

What happens when you stop?

Stopping has not been studied for either part, and nobody has studied stopping one while continuing the other. [10], [22]

• CJC-1295 with DAC: after two or three injections, the last on day 14, IGF-1 was still above its starting level on day 28. [11]
• Without DAC and ipamorelin: no data. After one IV dose, ipamorelin's growth-hormone pulse was gone within about 6 hours. [13]
• Related peptides: IGF-1 returned to baseline after a 14-day GHRH drip ended. [75]

In community education groups, people disagree on tapering versus stopping at once.

Premixed blend or separate vials?

A premixed blend is simpler, but it locks the ratio, hides which peptide caused a side effect, has never been tested for stability with both peptides mixed, and may not say which CJC-1295 it holds. Separate vials take more steps but keep each dose adjustable and traceable.

• Mixing and stability. No published study shows how long CJC-1295 and ipamorelin stay stable mixed in one vial or syringe. Sellers give storage times without test data. [56] Storage for each peptide alone is in its own guide. CJC-1295 storage · Ipamorelin storage
• The ratio is locked. In a 1:1 vial, raising CJC-1295 from 100 to 300 mcg also raises ipamorelin from 100 to 300 mcg. If CJC-1295 causes flushing and you halve the dose, you halve ipamorelin too. In a 1:2 or 1:4 compounded vial, the same draw carries two or four times as much ipamorelin as CJC-1295. [40], [2]
• Which CJC-1295. A blend with DAC is a weekly drug in a vial dosed nightly; the schedules do not transfer. Check the label, and ask the seller if it does not say. [10], [4]
• Tracking and troubleshooting. With separate vials, a reaction can be narrowed down to one peptide, as in the public account above. With a blend, it cannot. [63]
• Units. Pages write blend doses two ways. Some give the amount of each peptide ("250 mcg of each" is 500 mcg of blend powder) [40]; others give the blend total ("500 mcg of blend" is 250 mcg of each) [6]. Check which one a page means before working out syringe units for your own vial with the reconstitution calculator.

Common questions about the CJC-1295 and ipamorelin stack

What is the Hulk peptide blend?

It depends on the seller. Several sell CJC-1295 with ipamorelin as Hulk, either 5 mg + 5 mg without DAC or 10 mg + 10 mg with DAC. Others use the name for tesamorelin with ipamorelin, or for BPC-157 with TB-500. Read the label for each peptide and, for CJC-1295, which version. [3], [4], [16], [17]

Is CJC/Ipa with or without DAC?

Usually without DAC, but not always. Most blend pages that say name the version without DAC (Mod GRF 1-29); some sell a DAC blend, and many do not say. All human data are for the DAC version. [1], [7], [10]

Are GH Blend and Pulse the same as CJC/Ipa?

Yes, where the pages give contents. GH Blend and Pulse are 5 mg of CJC-1295 without DAC and 5 mg of ipamorelin per 10 mg vial, the common CJC/Ipa formula. One "GH Stack" is two separate vials. [6], [5], [15]

Does CJC-1295 with ipamorelin work better than either alone?

Nobody has tested it. Studies of other GHRH and ghrelin-type pairs, given as single IV doses or infusions of up to 24 hours, found more growth hormone than either alone. Whether that holds for these two peptides, injected nightly for weeks, or leads to any health benefit is unknown. [9], [39], [46]

Related guides

How this guide was researched

How this guide was made

This stack guide re-cites the original sources verified for the CJC-1295 and ipamorelin guides. New research covered what the combination raises: searches for any study of the pair, human studies of other growth-hormone peptide pairs, blend names and contents (more than 20 seller and clinic pages and lab reports), combination schedules and FDA inspection records. Community education groups informed how use is described; no private post is quoted or linked.

The research file holds 105 records, 101 verified against the original page; this guide cites 75. Seller pages are cited only for listed contents and their own claims, never as evidence of purity or effect. Drafting used AI assistance under Doserly's editorial rules, followed by source checks and editorial review. It is general education, not medical advice.

Explore the sources